Factors Affecting the Level of Glycosylated Hemoglobin in Patients with Diabetes: A Systematic Review

Introduction: Diabetes is considered to be the most commonly diagnosed disease of metabolic disorders and a global challenge. Given that hemoglobin glycosylated (HbA1C) shows us blood glucose over the past 8-12 weeks, and a Standard Criterion for long-term control of blood sugar. And was the need for a systematic study to examine the factors affecting this type of hemoglobin in diabetic patients. Therefore, this systematic review was conducted to determine the Factors affecting the level of glycosylated hemoglobin in patients with diabetes. Materials and Methods: The present study is a systematic review study that Searching articles on search engines, scholar, Embassy, Science direct, Google Scholar, and Pub Med in English and English were searched by search engines, sites and databases. Using the published articles in the last 25 years about the factors influencing the level of hemoglobin glycosylated in diabetic patients. In the first stage, 36 articles were found. Of these, 10 articles related to the topic that were published in the last 25 years were reviewed. Results: In this study, various studies were conducted. One of them was a study aimed at determining the effect of self-management program on blood glucose and glycosylated hemoglobin in patients with type 2 diabetes, showed that two months after the intervention, blood glucose and hemoglobin glycosylated in the intervention group improved was significantly before intervention. These changes were not seen in the control group. In addition, after intervention, there was a significant difference between the two groups in terms of glycosylated hemoglobin. Conclusion: The results of the studies showed the effective factors on glycosylated hemoglobin affect diabetic patients. One of them is a self-managed program which leads to improved blood glucose levels and decreased hemoglobin glycosylated levels in people with type 2 diabetes. And it can be said that selfmanagement promotion program can be used as a strategy to improve the health of the patients concerned.

Keywords: Hemoglobin glycosylated, Diabetes, Diabetic patients, HbA1C, Effective factors